As　the　largest　contemporary　platform　for　international　cooperation,　the　Belt　and　Road　Initiative　(BRI)　may　carry　the　risk　of　increasing　pressure　on　water,　energy　and　food　(WEF)　resources　while　driving　economic　development.　WEF　nexus　analyses　can　help　promote　green　and　sustainable　management　of　the　BRI＇s　resources,　but　has　received　little　attention.　Based　on　a　multi-regional　input-output　model,　this　study　identifies　key　points　of　WEF　nexus　management　in　the　BRI　from　WEF　utilization　efficiency,　final　demand　behavior　and　trade　inequality.　On　the　supply　side,　the　common　points　of　inefficiency　in　WEF　use　were　primarily　manufacturing　and　transport　and　communication　in　China　and　India,　chemicals　and　manufacturing　in　Russia,　and　chemicals,　manufacturing,　and　transport　and　communication　in　Iran.　Water　and　food　systems　were　closely　linked　through　the　planting　industry.　The　focus　for　adjustment　was　the　direct　water　and　land　use　efficiency　of　the　planting　industry　in　India　and　Pakistan.　On　the　final　demand　side,　household　consumption　drove　73.6%,　50.0%,　and　80.1%　of　WEF,　respectively;　particularly　richer　countries　(e.g.,　South　Korea　and　Italy)　had　more　serious　overconsumption　problems.　The　macro-control　points　of　investment　behavior　primarily　include　manufacturing,　construction,　and　transport　and　communication　in　China,　South　Korea,　Italy,　and　Russia.　With　the　reduction　of　trade　barriers,　countries　with　a　propensity　to　export,　particularly　those　with　resource　scarcity,　face　trade-offs　in　export　behavior　(e.g.,　exports　of　crops,　and　food　and　tobacco　from　China,　India　and　Pakistan).　Notably,　for　certain　resource-rich　economies,　such　as　Southeast　Asia,　Russia,　and　West　Asia,　improving　the　efficiency　of　relevant　sectors,　rather　than　restricting　exports,　is　the　priority.　In　bilateral　trade,　richer　countries　acquired　both　economic　and　resource　advantages,　whereas　countries　such　as　China,　India,　and　Pakistan　faced　serious　trade　inequalities.　Greener　and　more　equitable　WEF　development　in　the　BRI　could　be　better　promoted　through　strengthening　dialogue　and　cooperation　regarding　supply　and　demand　at　these　key　points.