Hydrogen-fueled　Wankel　rotary　engine　(HWER)　is　an　excellent　power　device　with　superior　power　and　emission　performances.　Besides,　unlike　hydrogen-fueled　reciprocating　piston　engines,　HWRE　is　less　prone　to　backfire　due　to　its　structural　advantages.　However,　limited　by　its　long　combustion　chamber,　knock,　one　of　abnormal　combustion　in　engines,　still　hinders　the　development　of　HWER.　Hence,　based　on　this　consideration,　the　goal　of　this　work　is　to　investigate　the　knock　of　HWRE　from　different　aspects,　including　ignition　timing,　spark　plug　number,　spark　plug　location,　excess　air　ratio　and　engine　speed,　to　provide　relevant　information　for　the　design　of　hydrogen　specific　WRE.　The　results　show　that　the　knock　intensity　gradually　increases　as　the　ignition　timing　is　advanced,　the　excess　air　ratio　is　decreased　and　the　engine　speed　is　increased,　but　the　knock　duration　shows　different　variations.　Adopting　dual　spark　plugs　tends　to　lead　to　stronger　knock　caused　by　unstable　combustion　of　hydrogen,　while　only　adopting　leading　spark　plug　tends　to　lead　to　the　knock　caused　by　auto-ignition.　When　dual　spark　plugs　are　used,　the　leading　spark　plug　is　more　responsible　for　the　knock　caused　by　unstable　combustion　and　the　trailing　spark　plug　is　more　responsible　for　the　knock　caused　by　auto-ignition.