A　prefabricated　structure　composed　of　a　lightweight　concrete　filled　steel　tube　(CFST)　frame　and　an　embedded　steel　plate　(ESP)　composite　wall　is　proposed,　known　as　a　CFST　frame-ESP　composite　wall.　To　study　the　seismic　performance　of　the　prefabricated　structure,　low　reversed　cyclic　loading　tests　of　six　full-scale　specimens　were　performed,　including　five　CFST　frame-ESP　composite　walls　with　different　wall　details　and　one　bare　frame.　The　failure　characteristics,　hysteretic　characteristics,　bearing　capacity,　stiffness　degradation,　and　energy　dissipation　capacity　of　the　specimens　were　compared,　and　a　simplified　model　was　used　for　the　ESP　composite　wall.　Based　on　OpenSees　finite　element　software,　finite　element　simulation　and　parameter　analysis　were　performed　using　a　simplified　model.　The　calculated　results　agree　well　with　the　experimental　results.　The　results　show　that　the　ESP　composite　wall　can　improve　the　bearing　capacity,　initial　stiffness,　and　energy　dissipation　capacity　of　the　CFST　frame　significantly.　The　use　of　a　rebar　brace　decreased　the　concrete　damage　and　increased　the　ultimate　bearing　capacity,　initial　stiffness,　and　energy　dissipation　capacity　of　the　ESP　composite　wall.　The　mechanical　characteristics　of　the　EPS　composite　wall　is　considered　in　the　simplified　model.　The　modeling　method　presented　herein　can　be　used　to　analyze　the　abovementioned　type　of　structure.