A　real-time　multiaxial　thermo-mechanical　damage　evaluation　method　was　proposed　under　variable　amplitude　loading.　In　order　to　achieve　real-time　damage　evaluation,　a　real-time　multiaxial　cycle　counting　method　that　can　take　into　account　temperature　loading　history　was　proposed.　The　proposed　multiaxial　cycle　counting　method　can　obtain　the　reversals　one　by　one　in　order　with　the　reading　of　the　load-time　history　data,　which　can　realize　the　damage　calculation　immediately　as　a　single　reversal　is　counted　out.　At　the　same　time,　to　consider　the　effect　of　temperature　loading　on　the　damage　accumulation,　an　equivalent　temperature　was　determined　for　the　time　period　of　the　counted　reversal.　A　fatigue-oxidation-creep　damage　model　that　can　consider　the　influence　of　the　non-proportional　additional　hardening　on　the　fatigue,　oxidation　and　creep　damages　was　used　to　predict　the　lives　in　cases　of　isothermal　axial-torsional　fatigue,　uniaxial　thermo-mechanical　fatigue　and　axial-torsional　thermo-mechanical　fatigue　under　constant　and　variable　amplitude　loadings.　The　results　showed　that　the　prediction　errors　were　within　a　factor　of　2.