Ultrasonic　cleaning　is　an　alternative　promising　method　to　control　the　membrane　fouling.　At　present,　the　urgent　task　of　further　promoting　its　application　is　to　establish　a　model　to　predict　the　instantaneous　membrane　flux.　In　this　study,　a　new　model　was　proposed　by　considering　the　power　intensity　and　temperature,　and　the　ultrasonic　cleaning　mechanism　was　revealed　with　ultrasonic　cavitation　theory　and　extended　Derjaguin-Landau-Verwey-Overbeek　(XDLVO)　theory.　Results　showed　that　the　predictions　of　the　model　were　in　good　agreement　with　the　experimental　data　(sigma　＜　1.23%)　for　the　polyethersulfone　(PES)　ultrafiltration　(UF)　membrane　fouled　with　humic　acid　(HA)　and　its　accuracy　was　higher　for　the　polyvinylidene　fluoride　(PVDF)　UF　membrane　(sigma　＜　0.72%)　or　actual　sewage　(sigma　＜　1.18%).　Meanwhile,　the　HA　cake　resistance　was　removed　79.10　similar　to　88.91%　and　the　corresponding　available　membrane　area　increased　0.42-0.57　times　within　1　min,　and　the　membrane　flux　recovery　(FR)　could　be　reached　to　91.07%　within　5　min　(100　W　and　30　degrees　C).　In　addition,　the　main　mechanism　of　ultrasonic　cleaning　was　that　the　kinetic　energy　of　the　ultrasonic　cavitation　microjet　(6.28　x10(-10)　J)　was　much　bigger　than　the　interaction　energy　between　the　HA　foulants　and　the　membrane　surface　(7.92　x10(-13)　J).