Piezoelectric　energy　harvesting　as　an　available　technology　for　realizing　self-powered　microsensors　has　attracted　increasing　attention.　However,　the　combination　of　large　piezoelectricity　and　high-temperature　stability　is　a　huge　challenge　in　perovskite　ceramics　for　developing　piezoelectric　energy　harvesters　(PEHs)　toward　wide-temperature　applications.　Herein,　a　stress　engineering　strategy　was　proposed　to　address　this　problem　by　combining　lattice　stress　and　heterogeneous　interface　stress.　Based　on　this　concept,　(Ni0.9Zn0.1)　TiO3-modified　Pb[(Zn1/3Nb2/3)(0.2)(Zr1/2Ti1/2)(0.8)]O-3　ceramic　achieves　both　enhanced　piezoelectricity　and　high-temperature　stability　(d(33)　=　485　pC/N　+/-　20%)　over　a　wide　temperature　range　of　24-250　degrees　C,　superior　to　the　pristine　counterpart　and　many　state-of-the-art　commercial　lead　zirconate　titanate-based　ceramics.　This　benefits　from　the　hierarchical　domains　with　high　piezoelectric　activity　and　temperature　stability　caused　by　stress　engineering.　Furthermore,　the　assembled　corresponding　PEH　not　only　successfully　drives　a　wireless　monitoring　and　alarm　system　but　also　exhibits　considerable　power　generation　capacities　(e.g.,　power　density　of　up　to　98.8　mu　W/cm(3))　even　at　250　degrees　C.　Our　work　may　provide　a　pathway　for　developing　high-performance　perovskite　materials　with　high　piezoelectricity　and　thermal　reliability　toward　high-temperature　piezoelectric　energy　harvesting.