收录:
摘要:
Classification of dynamic functional connectivity (DFC) is becoming a promising approach for diagnosing various neurodegenerative diseases. However, the existing methods generally face the problem of overfitting. To solve it, this paper proposes a convolutional neural network with three sparse strategies named SCNN to classify DFC. Firstly, an element-wise filter is designed to impose sparse constraints on the DFC matrix by replacing the redundant elements with zeroes, where the DFC matrix is specially constructed to quantify the spatial and temporal variation of DFC. Secondly, a 1x1 convolutional filter is adopted to reduce the dimensionality of the sparse DFC matrix, and remove meaningless features resulted from zero elements in the subsequent convolution process. Finally, an extra sparse optimization classifier is employed to optimize the parameters of the above two filters, which can effectively improve the ability of SCNN to extract discriminative features. Experimental results on multiple resting-state fMRI datasets demonstrate that the proposed model provides a better classification performance of DFC compared with several state-of-the-art methods, and can identify the abnormal brain functional connectivity.
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通讯作者信息:
来源 :
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
ISSN: 2168-2194
年份: 2022
期: 3
卷: 26
页码: 1219-1228
7 . 7
JCR@2022
7 . 7 0 0
JCR@2022
ESI学科: COMPUTER SCIENCE;
ESI高被引阀值:46
JCR分区:1
中科院分区:1
归属院系: