In　order　to　study　the　process　and　causes　of　air　pollution　in　Handan　City,　we　measured　the　inorganic　ion　and　carbon　component　to　analyze　the　variation　characteristics　of　PM2.5　from　samples　taken　at　the　site　of　Environmental　Monitoring　Center　of　Handan　was　selected　to　sample　the　PM2.5　concentrations　and　measure　the　inorganic　ion　and　carbon　component.　The　air　quality　model　of　WRF-CAMx　was　used　to　simulate　and　analyze　the　PM2.5　mass　concentration　contribution　of　different　emission　sources　in　various　regions　during　three　heavy　pollutions　in　autumn　and　winter　of　2017~2018.　The　results　showed　that　water-soluble　particles　accounted　for　62.4%　of　PM2.5　mass　concentration　in　Handan　during　heavy　pollution.　The　secondary　ions　showed　a　trend　of　NO3-＞　SO42-＞　NH4+.　During　the　three　continuous　heavy　pollution　processes　in　Handan　City,　the　pollution　was　affected　by　the　ground　uniform　pressure　field,　the　bottom　of　high　pressure　and　the　zonal　circulation　of　500hPa　at　high　altitude.　The　horizontal　and　vertical　transports　of　pollutant　were　inhibited.　The　decrease　of　boundary　layer　height　further　resulted　in　the　increase　of　PM2.5　mass　concentration.　The　three　heavy　pollutions　were　completely　removed　with　the　southward　move　of　Eastern　Siberia　high　pressure　and　Eurasian　Continental　high　pressure　and　increase　of　the　boundary　layer　height.　The　results　of　PSAT　tracer　module　showed　that　the　Fuxing　District,　Congtai　District　and　Yongnian　District　were　the　main　districts　and　counties　contributing　PM2.5　in　Handan　City,　with　the　total　contribution　ranging　from　66.8%　to　72.2%.　The　metallurgy,　mobile　source　and　residential　bulk　coal　combustion　were　the　three　major　pollution　sources　during　the　heavy　pollution　period.　©　2020,　Editorial　Board　of　China　Environmental　Science.　All　right　reserved.