Intermetallic　compounds　are　a　kind　of　important　materials　in　heterogeneous　catalysis.　In　this　work,　we　first　synthesized　the　PtMny　intermetallic　nanocrystals　using　the　polyvinyl　pyrrolidone-assisted　ethylene　glycol　reduction　method,　and　then　loaded　them　on　the　surface　of　mesoporous　CeO2(meso-CeO2)　derived　from　a　KIT-6-templating　route,　generating　the　mPt-nMnO(x)/meso-CeO2　(m　=　0　-　0.39　wt%,　n　=　0-1.21　wt%)　catalysts　after　calcination　at　500　degrees　C　in　air.　It　is　found　that　the　as-obtained　catalysts　displayed　an　ordered　mesoporous　architecture　with　surface　areas　of　95-108　m(2)/g.　The　0.37Pt-　0.16MnO(x)/meso-CeO2　sample　exhibited　the　best　catalytic　performance　for　toluene　combustion　(T50　%　=162　degrees　C　and　T90　%　=171　degrees　C　at　space　velocity　=　40,000　mL/(g　h)).　Kinetic　analysis　reveals　that　the　apparent　activation　energy　(57　kJ/mol)　obtained　over　the　best-performing　0.37Pt-　0.16MnO(x)/meso-CeO2　sample　was　lower　than　those　(63　-　75　kJ/mol)　obtained　over　the　other　samples.　Furthermore,　the　0.37Pt　-　0.16MnO(x)/meso-CeO2　sample　possessed　good　thermal　stability　and　water-resistant　performance.　Benzyl　alcohol,　benzoic　acid,　and　maleic　anhydride　were　proven　to　be　the　main　intermediates　of　toluene　combustion,　hence,　toluene　combustion　might　take　place　through　a　sequence　of　toluene　-＞　benzyl　alcohol　and　benzoic　acid　-＞　maleic　anhydride　-＞　carbon　dioxide　and　water,　which　might　obey　the　Eley　-　Rideal　reaction　mechanism.　It　is　concluded　that　loading　of　Pt　and　MnOx　enhanced　the　adsorbed　oxygen　and　Mn2+　species　concentration　and　low-temperature　reducibility,　thus　promoting　toluene　combustion　over　0.37Pt　-　0.16MnO(x)/meso-CeO2.