Air-supported　membrane　structures　are　being　widely　used　for　coal-sheds　or　the　enclosed　buildings　of　stockyards.　With　the　emergence　of　new　functional　requirements　for　buildings,　the　demand　for　an　increase　in　both　the　span　and　size　of　air-supported　membrane　structures　has　been　rapidly　increasing　in　China.　Till　now,　the　largest　span　and　length　of　structures　in　China　have　reached　200　m　and　1300　m　respectively.　For　air-supported　membrane　structures,　the　load-bearing　capacity　comes　from　the　difference　in　air　pressure　between　the　interior　and　exterior,　which　causes　the　structure　to　be　sensitive　to　wind　and　snow　loads.　This　paper　studies　the　wind-induced　response　of　a　constructed　air-supported　membrane　structure　for　a　coal-shed　cover　building　with　a　span　of　115　m　and　width　of　317　m,　which　is　located　in　the　southeast　coastal　city　of　Yueqing　in　Zhejiang　Province.　It　is　well　known　that　the　typhoon-induced　response　is　closely　related　to　the　safety　and　stability　of　the　structure.　To　ensure　the　safety　of　the　structure,　a　newly　improved　Structure　Health　Monitoring　System　(SHMS)　has　been　implemented　on　a　membrane　building　which　is　one　of　the　largest　scale　field　monitoring　projects　anywhere　in　the　world,　from　where　the　wind-induced　response　data　was　obtained　for　this　paper.　Based　on　the　measured　wind　speeds,　the　wind　pressure　distribution　coefficient　of　the　membrane　surface　is　derived　by　numerical　simulation　with　Fluent　software.　Meanwhile,　the　displacement　response　is　also　calculated　by　ANSYS　APDL.　Detailed　simulation　results　and　field　measurement　data　are　compared　for　the　displacement　response　caused　by　Typhoon　＂Chan-Thu＂.　It　is　shown　that　the　former　is　larger　than　the　latter　with　the　treatment　of　equivalent　wind　load.　However,　the　extreme　value　of　the　displacement　response　of　the　structure　with　consideration　of　fluctuating　wind　load　is　relatively　much　more　consistent　with　the　measured　value.　In　conclusion,　the　wind-induced　displacement　response　calculated　by　the　equivalent　static　wind　load　method　controlled　by　the　principle　of　maximum　displacement　equivalence　is　suitable　for　engineering　applications　and　wind　resistance　design,　which　will　result　in　a　slightly　higher　displacement　response　evaluation　than　the　real　cases.