Superhydrophobic　surfaces　are　important　in　many　applications　owing　to　their　special　properties　such　as　self-cleaning,　anti-icing,　antibacterial,　and　anti-fogging.　In　this　paper,　a　micro/nano　hierarchical　superhydrophobic　surface　with　a　low　roll-off　angle　was　created　on　304　stainless　steel.　The　water　contact　angle　was　measured　to　be　152　degrees　with　a　roll-off　angle　of　7.3　degrees.　Firstly,　microscale　bumps　were　created　by　femtosecond　laser　irradiation.　Secondly,　zinc　oxide　(ZnO)　nanowires　were　fabricated　on　the　laser-induced　bumps　using　a　hydrothermal　synthesis　method.　Results　show　that　after　laser　treatment　and　ZnO　nanostructuring,　the　stainless　steel　surface　became　superhydrophobic.　However,　the　roll-off　angle　of　this　hierarchical　structure　surface　was　larger　than　90　degrees.　To　reduce　the　surface　activity,　trimethoxy　silane　hydrophobic　coating　was　applied.　A　7.3　degrees　roll-off　angle　was　achieved　on　the　coated　surface.　The　underlying　mechanism　was　discussed.　The　hydrophobic　ZnO　structured　surface　can　help　prevent　bacterial　contamination　from　water,　which　is　important　for　implants.　Thus,　for　biomedical　applications,　the　antibacterial　property　of　this　hierarchical　surface　was　examined.　It　was　found　that　the　antibacterial　property　of　sample　surfaces　with　ZnO　nanowires　were　significantly　increased.　The　optical　density　(OD)　of　Escherichia　coli　(E.　coli)　attached　to　the　original　surface　was　0.93.　For　the　micro-structured　surface　(with　bumps),　the　OD　was　0.9,　and　for　the　hierarchical　surface　(with　bump　&　nanowires),　it　was　0.54.　For　nanostructured　ZnO　nanowire　surface,　the　OD　was　only　0.09.　It　demonstrates　good　antibacterial　properties　of　ZnO　nanowires.