Molten　salt　as　heat　transfer　and　thermal　storage　medium　is　wildly　used　in　concentrating　solar　power　plant　(CSP).　At　present,　the　traditional　shell-and-tube　heat　exchanger　is　commonly　used　in　CSP.　So　far,　the　research　on　shutter　baffle　heat　exchanger　with　twisted　tube　(SBHX-TT)　of　molten　salt　based　nanofluids　is　relatively　few.　In　this　work,　the　flow　and　heat　transfer　characteristics　of　molten　salt　based　nanofluids　in　SBHX-TT　with　different　geometric　parameters　are　studied.　The　heat　transfer　coefficient,　pressure　drop,　comprehensive　evaluation　index　and　synergistic　field　are　comparetively　analyzed.　The　results　show　that　when　Re　is　between　3487　and　20,924,　the　convective　heat　transfer　coefficient　increases　with　the　decrease　of　the　inclination　angle　and　the　ratio　of　baffle　pitch　to　grille　sheet　width　(Y),　the　pressure　drop　also　concurrently　increases.　When　Y　=　4,　the　baffle　inclination　angle　is　30　degrees,　the　convective　heat　transfer　maximally　increases　by　104.4%　and　the　pressure　drop　increases　by　174.2%　compared　with　that　without　baffle.　Through　response　surface　analysis,　the　obtained　highest　comprehensive　evaluation　index　is　1.51,　when　the　grille　sheet　inclination　angle　is　36　degrees　and　baffle　pitch　to　grille　sheet　width　is　5.