In　the　fields　of　organ　printing　and　drug　preparation,　high-precision　and　stable　dispersion　of　high-viscosity　biomaterials　enable　precise　control　of　organ　morphology　and　drug　release　rate.　This　paper　proposes　the　use　of　an　acoustic　surface　wave　to　overcome　the　problem　of　unstable　interface　breakup　and　weak　size　controllability　when　the　traditional　passive　droplet　microfluidics　is　applied　to　high-viscosity　(higher　than　0.4　Pa　&　BULL;s)　dispersed　phases.　This　paper　studies　the　internal　flow　behavior　of　high-viscosity　fluid　under　the　influence　of　an　acoustic　field　and　realizes　the　accurate　prediction　of　formation　regime　and　droplet　size.　Experimental　results　show　that　with　the　increase　in　acoustic　power,　three　unique　droplet　generation　regimes　(e.g.,　long　jetting,　transition,　and　dripping)　exist.　The　transition　regime　is　most　suitable　for　high-throughput　preparation　of　high-viscosity　droplets,　and　its　corresponding　flow　and　acoustic　conditions　can　be　predicted　by　equation　mu(d)/mu(c)　=　4.8　x　10(-8)　(mu(c)　x　v(c)/A　P　0　2　x　w)(-3.32).　Affected　by　the　regime　transition,　the　droplet　size　increases　with　the　increase　in　acoustic　power.　The　droplet　size　prediction　can　be　realized　based　on　the　capillary　number　Ca-f,　which　represents　the　intensity　of　the　acoustic　field.　Published　under　an　exclusive　license　by　AIP　Publishing.