Deoxynivalenol　(DON),　which　is　known　as　one　of　the　most　harmful　mycotoxins,　has　contaminated　food　and　feed　and　attracted　concerns　worldwide.　However,　the　effective　adsorptive　removal　of　DON　to　ensure　food　safety　still　is　a　challenge,　which　is　ascribed　to　the　poor　planarity　and　larger　steric　hindrance　of　DON　molecules.　Here,　a　new　Zr(IV)-based　metal-organic　framework,　entitled　BUT-16　with　one-dimensional　channels　and　N-atom-decorated　pore　surface,　is　designed,　prepared,　and　utilized　for　the　adsorptive　removal　of　DON.　It　exhibits　excellent　adsorption　ability　with　an　adsorption　capacity　of　46　mg/g　higher　than　all　reported　adsorbents　until　now　and　a　rapid　adsorption　rate　of　0.031　g　mg(-1)　min(-1).　DFT　calculation　and　X-ray　photoelectron　spectroscopy　results　of　the　guest-loaded　phase　suggest　that　the　record-breaking　adsorption　could　be　due　to　the　cooperation　of　hydrogen　bonding　and　Zr　center　dot　center　dot　center　dot　O　interaction　between　DON　molecules　and　BUT-16　host.　Most　importantly,　BUT-16　can　effectively　adsorb　and　remove　DON　in　the　simulated　gastric　fluid,　but　DON　adsorbed　on　BUT-16　is　hardly　desorbed　in　the　simulated　intestinal　fluid.　The　results　demonstrate　that　BUT-16　has　great　promising　application　for　the　control　of　DON　in　foods　and　feeds.