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作者:

Mao, Boyan (Mao, Boyan.) | Feng, Yue (Feng, Yue.) | Duan, Mengyao (Duan, Mengyao.) | Dong, Yihang (Dong, Yihang.) | Li, Gaoyang (Li, Gaoyang.) | Li, Bao (Li, Bao.) | Liu, Jincheng (Liu, Jincheng.) | Guo, Yuting (Guo, Yuting.) | Wei, Minghui (Wei, Minghui.) | Zhao, Zhou (Zhao, Zhou.) | Liu, Youjun (Liu, Youjun.) (学者:刘有军)

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Scopus SCIE

摘要:

Objective: After coronary artery bypass grafting (CABG) surgery, the main causes of poor instant patency of left internal mammary arteries (LIMAs) are competitive flow and anastomotic stenosis, but how to determine the cause of LIMA non-patency without interfering with the native coronary artery is still a difficult problem to be solved urgently.Methods: In this study, a 0D-3D coupled multiscaled CABG model of anastomotic stenosis and competitive flow was constructed. After calculation, the flow waveform of the LIMA was extracted, and the waveform shape, common clinical parameters (average flow, PI, and DF), and graft flow FFT ratio results (F0/H1 and F0/H2) were analyzed.Results: For LIMA, these three common clinical parameters did not differ significantly between the anastomotic stenosis group and competitive flow group. However, the waveform shape and FFT ratio (especially F0/H2) of the competitive flow group were significantly different from those of the anastomotic stenosis group. When the cause was competitive flow, there was systolic backflow, and F0/H2 was too high (>14.89). When the cause was anastomotic stenosis, the waveform maintained a bimodal state and F0/H2 was in a normal state (about 1.17).Conclusion: When poor instant patency of the LIMA is found after CABG, the causes can be determined by graft flow waveform shape and F0/H2.

关键词:

graft patency multiscaled model lumped parameter model computational fluid dynamics coronary artery bypass grafting

作者机构:

  • [ 1 ] [Mao, Boyan]Beijing Univ Chinese Med, Sch Life Sci, Beijing, Peoples R China
  • [ 2 ] [Duan, Mengyao]Beijing Univ Chinese Med, Sch Life Sci, Beijing, Peoples R China
  • [ 3 ] [Dong, Yihang]Beijing Univ Chinese Med, Sch Life Sci, Beijing, Peoples R China
  • [ 4 ] [Wei, Minghui]Beijing Univ Chinese Med, Sch Life Sci, Beijing, Peoples R China
  • [ 5 ] [Feng, Yue]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing, Peoples R China
  • [ 6 ] [Li, Bao]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing, Peoples R China
  • [ 7 ] [Liu, Jincheng]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing, Peoples R China
  • [ 8 ] [Liu, Youjun]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing, Peoples R China
  • [ 9 ] [Feng, Yue]Peking Univ First Hosp, Med Equipment Dept, Beijing, Peoples R China
  • [ 10 ] [Li, Gaoyang]Tohoku Univ, Inst Fluid Sci, Sendai, Japan
  • [ 11 ] [Guo, Yuting]Tohoku Univ, Inst Fluid Sci, Sendai, Japan
  • [ 12 ] [Zhao, Zhou]Peking Univ, Cardiac Surg Dept, Peoples Hosp, Beijing, Peoples R China

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来源 :

FRONTIERS IN PHYSIOLOGY

年份: 2022

卷: 13

4 . 0

JCR@2022

4 . 0 0 0

JCR@2022

ESI学科: BIOLOGY & BIOCHEMISTRY;

ESI高被引阀值:43

JCR分区:2

中科院分区:2

被引次数:

WoS核心集被引频次: 2

SCOPUS被引频次: 3

ESI高被引论文在榜: 0 展开所有

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中文被引频次:

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