Rapid　and　effective　detection　of　pesticide　residues　from　complex　surfaces　of　fruits　and　vegetables　has　important　significance.　Herein,　we　report　a　novel　three-dimensional　(3D)　hierarchical　porous　functional　surface-enhanced　Raman　scattering　(SERS)　substrate,　which　is　fabricated　by　successive　two-step　hydrothermal　synthesis　strategy　of　silver　nanoparticles　(Ag　NPs)　and　cobalt　oxide　nanowires　(Co3O4　NWs)　on　the　3D　copper　foam　framework　as　Cu@Co3O4@Ag-H.　The　strategy　offers　a　new　avenue　for　localized　plasmonic　materials　distribution　and　construction,　which　exhibits　better　morphology　regulation　ability　and　SERS　activity　(or　hotspots　engineering)　than　physical　spurring　obtained　Cu@Co3O4@Ag-S.　The　developed　Cu@Co3O4@Ag-H　possesses　large　surface　area　and　rich　hotspots,　which　contributes　to　the　excellent　SERS　performance,　including　homogeneity　(RSD　of　7.8%),　sensitivity　(enhancement　factor,　EF　of　2.24　x　10(8))　and　stability.　The　Cu@Co3O4@Ag-H　not　only　provides　plenty　of　Electromagnetic　enhancement　(EM)　hotspots　but　also　the　trace　detection　capability　for　droplet　rapid　sensing　within　2　s.　Cu@Co3O4@Ag-H　substrate　is　further　developed　as　an　effective　SERS　sensing　platform　for　pesticide　residues　detection　on　the　surfaces　of　fruits　and　vegetables　with　excellent　LOD　of　0.1　ppm,　which　is　lower　than　the　most　similar　reported　works.　This　work　offers　new　potential　for　bioassay,　disease　POCT　diagnosis,　national　security,　wearable　flexible　devices,　energy　storage　and　other　related　fields.