According　to　the　current　seismic　design　code,　it　is　possible　not　to　obtain　the　expected　failure　mechanism　of　＇strong　column　and　weak　beam＇　for　reinforced　concrete　(RC)　frame　structures　without　infill　walls　at　the　bottom.　The　equivalent　diagonal　bracing-frame　model　was　established　to　consider　the　interaction　between　the　infill　wall　and　frame　members.　Calculation　of　equivalent　damping　ratio　and　the　equivalent　stiffness　were　improved　for　an　equivalent　single-degree-of-freedom　system.　The　displacement-based　seismic　design　method　was　presented　for　RC　frame　structures　with　infill　wall.　Aiming　at　different　performance　levels　for　a　five　story　RC　frame　structure　without　infill　walls　at　the　bottom,　displacement-based　seismic　performance　design　were　carried　out　in　order　to　satisfy　the　performance　levels　of　serviceability,　life-safety,　and　collapse　prevention　by　means　of　structural　pushover　analysis.　Furthermore　it　is　proved　that　this　method　is　feasible　by　means　of　both　capacity　spectrum　method　and　dynamic　elasto-plastic　time　history　analysis　method.　Therefore　it　can　be　shown　that　performance-based　seismic　design　can　be　achieved　by　taking　both　advantages　and　disadvantages　of　infill　walls　to　the　frame　members　into　account　by　means　of　the　advanced　displacement-based　seismic　design　method.　©　2019,　Editorial　Office　of　Journal　of　Building　Structures.　All　right　reserved.