A　coupled　thermo-hydro　model　is　developed　for　optimizing　heat　mining　strategies　in　a　fractured　geothermal　reservoir　by　incorporating　material　compressibility　and　fracture　deformation.　Governing　equations　for　the　three-dimensional　fluid　flow　and　heat　transmission　processes　in　terms　of　local　thermal　non-equilibrium　concept　are　discretized　using　a　unified　pipe　network　method.　The　influence　of　fracture　deformation　on　the　distribution　of　fluid　temperature　is　investigated　using　a　near-wellbore　reservoir　model.　The　development　optimization　of　a　geothermal　reservoir　at　Gro　beta　Schonebeck　is　performed　by　evaluating　heat　production　over　60　years.　Several　strategies　are　designed　that　involve　changing　the　arrangement　of　a　new　horizontal　wellbore　and　hydraulic　stimulations.　Simulation　results　for　the　different　strategies,　including　the　outlet　fluid　temperature　drawdown,　thermal　breakthrough　time,　and　net　heat　extraction　rate,　are　analysed.　Strategies　with　poor　fracture　connections　feature　relatively　low　flow　rates　and　accumulated　thermal　production.　Strategy　3　to　Strategy　6　greatly　improve　the　accumulated　thermal　production　by　enhancing　fluid　circulation　in　fracture-connected　systems.　Heat　mining　efficiency　can　be　improved　if　a　new　wellbore　is　designed　in　the　high-permeability　formation　and　the　discontinuities　maintain　high　hydraulic　connectivity　for　fluid　circulation.　This　study　provides　a　numerical　method　for　optimizing　geothermal　development　strategies　in　terms　of　economic　benefits.　(C)　2019　Elsevier　Ltd.　All　rights　reserved.