Tinnitus　is　associated　with　abnormal　functional　connectivity　of　multiple　regions　of　the　brain.　However,　previous　analytic　methods　have　disregarded　information　on　the　direction　of　functional　connectivity,　leading　to　only　a　moderate　efficacy　of　pretreatment　planning.　We　hypothesized　that　the　pattern　of　directional　functional　connectivity　can　provide　key　information　on　treatment　outcomes.　Sixty-four　participants　were　enrolled　in　this　study:　eighteen　patients　with　tinnitus　were　categorized　into　the　effective　group,　twenty-two　patients　into　the　ineffective　group,　and　twenty-four　healthy　participants　into　the　healthy　control　group.　We　acquired　resting-state　functional　magnetic　resonance　images　prior　to　sound　therapy　and　constructed　an　effective　connectivity　network　of　the　three　groups　using　an　artificial　bee　colony　algorithm　and　transfer　entropy.　The　key　feature　of　patients　with　tinnitus　was　the　significantly　increased　signal　output　of　the　sensory　network,　including　the　auditory,　visual,　and　somatosensory　networks,　and　parts　of　the　motor　network.　This　provided　critical　insights　into　the　gain　theory　of　tinnitus　development.　The　altered　pattern　of　functional　information　orchestration,　represented　by　a　higher　degree　of　hypervigilance-driven　attention　and　enhanced　multisensory　integration,　may　explain　poor　clinical　outcomes.　The　activated　gating　function　of　the　thalamus　is　one　of　the　key　factors　for　a　good　prognosis　in　tinnitus　treatment.　We　developed　a　novel　method　for　analyzing　effective　connectivity,　facilitating　an　understanding　of　the　tinnitus　mechanism　and　treatment　outcome　expectation　based　on　the　direction　of　information　flow.