This　paper　presents　an　experimental　investigation　of　the　dynamic　moment-rotation　relationship　of　flexure　-critical　RC　columns　under　low-velocity　impact.　Impact　tests　of　RC　columns　were　conducted　and　an　accelera-tion　measurement　scheme　was　proposed　to　estimate　the　inertial　force　of　the　column　during　the　impact.　The　true　flexural　strength-rotation　relationships　of　RC　columns　under　impact　loading　were　obtained,　which　indicates　that　the　flexural　strength　and　ultimate　deformation　of　the　column　increased　due　to　the　strain　rate　effects　when　compared　with　the　quasi-static　results　simultaneously　conducted　in　this　paper.　The　influence　of　strain　rate　and　main　structural　parameters　on　the　moment-rotation　relationship　of　the　RC　column　was　analyzed.　Finite　element　(FE)　techniques　to　predict　the　impact　resistance　of　RC　columns　were　then　validated　based　on　the　experimental　results,　followed　by　a　parametric　study　to　investigate　the　effects　of　impact　velocity,　longitudinal　reinforcement　ratio　and　axial　force　ratio　on　the　moment-rotation　relationships　of　RC　columns.　Finally,　experimental　and　nu-merical　results　were　used　to　develop　an　empirical　model　to　predict　the　dynamic　moment-rotation　relationship　of　bridge　piers　under　low-velocity　impact.　These　findings　drawn　from　the　experimental　and　numerical　in-vestigations　can　facilitate　to　predict　the　dynamic　moment-rotation　relationship　of　RC　columns　subjected　to　vessel　impacts.