Integrating　toxic　fungicide　into　a　functional　stimuli-responsive　nanosystem　can　effectively　improve　the　fungus　control　specificity　and　reduce　the　effect　on　non-target　organisms.　We　report　here　a　redox　and　cellulase　dual-responsive　multifunctional　nanoparticle　based　on　bimodal　mesoporous　silica　(BMMs)　to　deliver　prochloraz　(Pro)　for　the　smart　management　of　wilt　disease　(Pro-AC-SS-BMMs,　known　as　P-ASB).　The　surface　of　the　nanocarrier　was　modified　with　an　aminosilane　coupling　agent,　and　Pro　was　encapsulated　by　physical　adsorption　using　2,2　＇-dithiodiacetic　acid　as　a　smart　bridge　and　disulfide　(SS)　cross-linked　aminocellulose　(AC)　as　gatekeepers.　P-ASB　nanoparticles　(NPs)　had　a　spherical　structure,　and　the　size　was　531.2　+/-　4.9　nm.　The　loading　rate　of　Pro　was　28.5%,　and　the　NPs　possessed　excellent　redox/cellulase　dual-responsive　release　characteristics　in　the　presence　of　glutathione　(GSH)　and　cellulase.　The　nanocarrier　could　effectively　protect　Pro　against　photodegradation　and　had　better　foliar　wettability　than　the　Pro　technical.　Fluorescence　tracer　results　showed　that　the　nanocarriers　were　taken　up　and　activated　by　the　mycelium.　P-ASB　NPs　had　better　control　efficacy　against　Rhizoctonia　solani　and　had　no　significant　toxicity　to　cells　and　bacteria.　This　study　provides　a　new　strategy　for　enhancing　the　environmental　protection　and　promoting　the　development　of　green　agriculture.