The　statistical　data　of　earthquake　hazard　indicate　that　the　liquefaction　and　large　lateral　flow　deformation　of　ground　is　one　of　the　main　reasons　of　pile　foundation　failure.　It　is　significant　to　focus　on　the　seismic　dynamic　behavior　of　pile　foundation　in　inclined　liquefiable　soil.　Based　on　the　Opensees　finite　element　platform,　an　in-tegrated　finite　numerical　model　of　inclined　liquefiable　soil-pile　group-structure　interaction　is　established　in　this　study,　according　to　the　shaking　table　model　test　of　inclined　liquefiable　soil.　The　nonlinearity　of　pile-soil　contact　and　the　shear　localization　of　soil　layer　are　considered　in　the　numerical　simulation.　The　comparison　of　the　nu-merical　simulation　result　with　the　shaking　table　test　results　are　verified.　In　order　to　discuss　the　influence　of　different　overlying　soil　layer　on　the　seismic　behavior　of　soil　and　pile　system,　a　typical　inclined　liquefiable　soil-pile　group-structure　interaction　finite　element　model　is　established　by　the　proposed　numerical　simulation　method.　The　results　show　that　the　overlying　soil　layer　has　an　obvious　influence　on　the　seismic　dynamic　behavior　of　the　pore　pressure,　the　horizontal　displacement　of　soil　and　pile.　The　increase　of　the　thickness　of　overlying　soil　can　reduce　the　liquefaction　degree　of　sand　and　improve　the　mechanical　performance　of　pile　foundation.