Herein,　we　fabricated　a　single　metal　atom　oxide　(W,　Cu　and　Co)　anchored　on　the　interstitials　atomic　line　of　BiVO4　with　reduced　graphene　oxide　(rGO-ED-BiVO4-WCuCo)　by　simple　sonication　process,　which　demonstrated　a　good　photocatalytic　degradation　of　organic　contaminants.　Through　examination　of　the　physical　and　chemical　characteristics　of　the　prepared　material　discovered　that　the　higher　density　loading　of　single　metal　atom　oxide　(SMAO)　uniformly　on　interstitials　atomic　line　of　BiVO4　improved　its　ability　to　absorb　visible　light.　The　photocatalytic　efficiency　of　nanocomposites　has　been　evaluated　in　the　presence　of　visible　light　using　the　model　chemicals　norfloxacin　(NF)　and　rhodamine　B　(RB).　Comparison　of　pristine　heteropoly　acid,　BiVO4,　and　nanocomposites　rGO-ED-BiVO4-WCo-30,　rGO-ED-BiVO4-WCu-30　and　rGO-ED-BiVO4-WCuCo-20,　demonstrated　that　employing　rGO-ED-BiVO4-WCuCo-30　increased　the　degradation　efficiency　of　NF　and　RB　to　95.6%　and　97.8%,　proving　that　W/Cu/Co　deposition　is　a　useful　method　for　boosting　BiVO4＇s　photocatalytic　activity.　The　enhanced　electron　transfer　capacity　may　be　attributed　in　large　part　to　the　incorporation　of　W,　Cu,　and　Co　oxide,　which　acts　as　a　potent　electron　driving　force.　After　five　cycles　of　reusing　rGO-ED-BiVO4-WCuCo-30,　a　slight　decrease　in　the　degradation　efficiency　was　noticed.　LC-MS　identified　the　generation　of　possible　intermediates　along　the　norfloxacin　degradation　pathway.　Overall,　a　simple　technique　to　synthesize　SMAO　catalysts　for　the　visible　light　mediated　heterogeneous　photocatalytic　degradation　of　pharmaceutical　and　dye　contaminants　is　reported.