Partial　nitrification-anammox　(PN/A)　is　an　energy-efficient　process　for　nitrogen　removal　from　sewage.　The　influent　organics　of　sewage　is　usually　pre-removed,　reducing　the　risk　for　enriching　anammox　bacteria　(AnAOB).　However,　recent　studies　demonstrate　that　optimum　influent　organics　could　improve　nitrogen　removal　and　operational　stability　of　PN/A.　Thus,　the　impact　of　organics　on　PN/A-based　process　should　not　be　overlooked.　In　this　review,　the　complicated　impacts　of　organics-containing　influent　on　anammox　and　their　linking　to　apply　PN/A　are　discussed.　Firstly,　the　effect　of　organics　on　AnAOB　metabolism　and　the　competition　relationship　between　AnAOB　and　heterotrophic　bacteria　are　summarized.　Secondly,　the　combined　effects　of　influent　organics　and　operational　strategies　on　PN/A-based　process　were　reviewed.　Thirdly,　how　to　control　influent　organics　in　the　real　application　of　PN/A　were　discussed.　Lastly,　recent　development　of　the　PN/A-based　process　combined　with　denitrification　were　reviewed.　Overall,　influent　organics　could　be　an　essential　factor　for　successful　application　of　sewage　PN/A.