In　the　saturated　soil-pile　foundation-superstructure　system,　different　controlling　equations　and　temporal　integrator　methods　of　pile　foundation,　superstructure　and　saturated　soil　lead　to　inconvenient　calculation　by　using　the　finite　element　method.　An　interactive　computational　method　for　the　saturated　soil-structure　interaction　problem　is　developed　using　on　the　Client-Server　technique.　In　this　method,　the　dynamic　responses　of　the　saturated　soil　subsystem　and　pile　foundation-superstructure　subsystem　are　calculated　in　two　subroutines　respectively.　The　forces　and　displacements　are　transferred　by　common　nodes　of　the　two　subsystems.　The　completed　explicit　temporal　integrator　method　is　introduced　to　determine　the　u-p　relationship　of　the　saturated　soil　subsystem.　It　significantly　improves　the　computational　efficiency.　In　numerical　example,　the　proposed　method　is　compared　with　the　Newmark　method.　And　the　proposed　method　is　demonstrated　as　an　effective　tool　to　solve　the　seismic　responses　of　the　saturated　soil　site-pile　foundation-superstructure　system.　©　2018,　Science　Press.　All　right　reserved.