In　order　to　realize　the　industrialization　of　nitrifying　bacteria　enrichment　cultivation　and　large-scale　application　of　entrapment　immobilization,　activated　sludge　from　a　sewage　treatment　plant　was　used　as　the　seed　sludge.　The　concentration　of　substrate　was　increased　progressively　in　an　industrialized　tank.　Nitrifying　bacteria　were　grown　rapidly　by　controlling　the　concentration　of　FA　and　FNA,　and　the　ammonia　oxidation　rate　reached　118　mg•(L•h)-1　eventually.　The　results　of　high-throughput　sequencing　showed　that　Nitrosomonas,　nitrifying　bacteria,　was　only　0.53%　of　the　bacteria.　After　exposing　it　to　an　enrichment　culture,　the　content　of　Nitrosomonas　rose　to　10.27%,　20　times　larger　than　that　in　the　raw　sludge.　Diversity　was　significantly　smaller　at　the　same　time.　After　embedding　immobilization　with　PVA　(polyvinyl　alcohol),　the　embedded　fillers　nitrification　load　was　30%.　A　continuous-flow　approach　was　utilized　in　the　recovery　phase,　and　the　nitrification　loading　rate　reached　a　high　level,　62　mg•(L•h)-1,　and　efficient　recovery　of　the　biologically　active　fillers　was　achieved.　©　2018,　Science　Press.　All　right　reserved.