In　order　to　investigate　the　application　of　lattice　Boltzmann　method　(LBM)　in　the　numerical　simulation　of　computed　tomography　angiography-derived　fractional　flow　reserve　(FFRCT),　an　idealized　narrowed　tube　model　and　two　coronary　stenosis　arterymodels　are　studied.　Based　on　the　open　source　code　library　(Palabos),　the　relative　algorithm　program　in　the　development　environment　(Codeblocks)　was　improved.　Through　comparing　and　analyzing　the　results　of　FFRCT　which　is　simulated　by　LBM　and　finite　element　analysis　software　ANSYS,　and　the　feasibility　of　the　numerical　simulation　of　FFRCT　by　LBM　was　verified.　The　results　show　that　the　relative　error　between　the　results　of　LBM　and　finite　element　analysis　software　ANSYS　is　about　1%,　which　vertifies　the　feasibility　of　simulating　the　coronary　FFRCT　by　LBM.　The　simulation　of　this　study　provides　technical　support　for　developing　future　FFRCT　application　software,　and　lays　the　foundation　for　the　calculation　of　clinical　FFRCT.　Copyright　©　2018　by　Editorial　Office　of　Journal　of　Biomedical　Engineering.