The　overall　dynamic　response　of　28-story　frame-shear　wall　structure　is　studied　through　field　test　and　numerical　analysis　based　on　the　blasting　engineering　of　subway　tunnel.　The　blasting　vibration　monitoring　and　natural　excitation　test　are　used　for　field　test.　Ibrahim　time　domain(ITD)　method　is　used　to　determine　the　modal　frequencies　and　modal　damping　ratio　of　structure　to　provide　the　basis　for　further　analysis　of　the　vibration　response　laws.　The　structure　is　simplified　into　a　mass-spring-damper　model.　Based　on　the　modal　parameters　identified　in　the　tests,　the　stiffness　matrix　and　damping　matrix　of　mass-spring-damper　model　are　fixed,　and　the　dynamic　differential　equation　is　set　up,　thus　calculating　the　modal　parameters　and　frequency　response　functions　of　the　building　bending　vibration.　Simulink　dynamic　simulation　model　is　established　based　on　the　dynamic　differential　equation　of　mass-spring-damper　model.　The　overall　vibration　response　law　of　high-rise　buildings　under　the　action　of　tunnel　blasting　seismic　is　analyzed　by　taking　the　velocity　signal　of　blasting　vibration　as　exciting　signal.　The　results　show　that　the　vertical　vibration　is　the　largest,　the　longitudinal　vibration　is　the　second　and　the　tangential　vibration　is　the　smallest　under　the　action　of　blasting　vibration　of　subway　tunnel,　and　the　lateral　vibration　velocity　is　not　much　different　from　the　tangential　vibration　velocity　at　the　higher　floors;　on　the　higher　floors,　the　vibration　velocity　peak　fluctuates　with　the　increase　in　floor　and　is　interrelated　to　the　main　modal　shape,　and　the　peak　distribution　of　vibration　velocities　shows　this　correlation;　and　the　high-rise　building　is　simplified　to　a　mass-spring-damper　model,　and　a　mathematical　model　of　dynamic　reaction　is　set　up,　and　then　Simulink　simulation　model　is　established　for　simulation　calculation.　This　method　can　effectively　predict　the　response　of　the　structure　under　blasting　vibration.　©　2018,　Editorial　Board　of　Acta　Armamentarii.　All　right　reserved.