Selective　laser　melting　(SLM)　is　emerging　as　a　promising　3D　printing　method　for　orthopedic　and　dental　applications.　However,　SLM-based　Ti6Al4V　components　frequently　exhibit　high　roughness　values　and　partial　surface　defects.　Laser　polishing　(LP)　is　a　newly　developed　technology　to　improve　the　surface　quality　of　metals.　In　this　research,　LP　is　applied　to　improve　the　surface　finish　of　components.　The　results　show　that　the　laser　beam　can　neatly　ablate　the　aggregates　of　metallic　globules　and　repair　cracks　and　pores　on　the　surface,　resulting　in　a　smooth　surface　with　nanocomposites.　Overall,　the　results　indicate　that　using　LP　optimizes　surface　morphology　to　favor　fatigue　behavior　and　osteoblastic　differentiation.　These　findings　provide　foundational　data　to　improve　the　surface　roughness　of　a　laser-polished　implant　and　pave　the　way　for　optimized　mechanical　behavior　and　biocompatibility　via　the　laser　process.