To　develop　environment-friendly,　highly-efficient　precast　bridge　structures　suitable　for　moderate-to-high　seismic　regions,　two　novel　precast　segmental　CFST　bridge　piers　with　bolted　connections　were　proposed.　The　quasi-static　lateral　cyclic　loading　test　on　the　aforementioned　precast　segmental　CFST　bridge　piers　with　and　without　axial　prestress　was　carried　out　to　investigate　and　analyze　the　nonlinear　behavior,　including　the　resilience-displacement　hysteretic　behavior,　unloading　stiffness,　prestress　loss　in　tendons,　joint　opening.　The　structural　deformation　and　damage　process　of　precast　segmental　CFST　bridge　piers　under　the　cyclic　loading　was　briefly　described.　The　results　show　that　the　precast　segmental　CFST　bridge　piers　with　bolted　connections　can　provide　the　favorable　lateral　bearing　capacity,　the　excellent　energy　dissipation　capacity,　plump　hysteretic　curves　and　the　appropriate　ductility.　The　self-resetting　capability　of　precast　segmental　CFST　bridge　piers　can　be　improved　by　axially　post-tensioned　unbounded　prestress.　Compared　with　the　opening　situation　at　the　bottom　of　traditional　assembled　piers,　the　uniform　distribution　of　joint　opening　between　adjacent　segments　will　be　attained　by　the　reasonable　detail　design　of　connecting　pipes　to　make　the　best　of　the　segmental　strength.　The　axial　prestress　tension　extends　linearly　with　the　increase　of　the　horizontal　loading　displacement　drift.　The　adequate　lateral　strength　of　the　precast　segmental　CFST　bridge　piers　with　bolted　connections　is　revealed　with　horizontal　displacement　drift　of　7.7%,　and　the　prestress　loss　in　strands　is　about　20%　of　the　initial　tension　force　after　removing　the　lateral　loading　action.　The　results　will　provide　references　for　the　structural　design　and　engineering　practice　of　precast　segmental　CFST　bridge　piers,　with　a　positive　meaning　for　R　&　D　of　accelerated　bridge　construction.　©　2017,　Editorial　Department　of　China　Journal　of　Highway　and　Transport.　All　right　reserved.