The　separation　of　C2H4　from　C2H6/C2H4　mixture　is　of　great　importance　but　difficult　and　energy　intensive.　Adsorptive　separation　provides　an　alternative　approach　to　ameliorate　this　situation.　Here,　we　report　a　microporous　metal-organic　framework　(MOF)　BUT-315-a　as　a　C2H6-se-lective　adsorbent　for　the　separation　of　C2H6/C2H4　gas　mixture.　BUT-315-a　combines　good　IAST　selectivity　of　2.35　with　high　C2H6　uptake　of　97.5　cm3　g-1,　giving　superior　high　separation　potential　DQ　(2226　mmol　L-1)　for　equimolar　C2H6/C2H4　at　298　K.　Impressively,　such　excellent　performance　can　be　preserved　at　higher　temperatures　of　313　and　323　K　to　accommodate　industrial　conditions.　Efficient　dynamic　separation　performance　of　BUT-315-a　has　been　demonstrated　by　column　breakthrough　experiments　under　varied　temperatures　and　gas　ratios.　Theoretical　calculations　further　reveal　multiple　synergistic　interactions　between　C2H6　and　the　framework.　This　work　highlights　a　new　benchmark　material　for　C2H6/C2H4　separation　and　provides　guidance　for　designing　adsorbent　for　separation　applications.(c)　2023　Institute　of　Process　Engineering,　Chinese　Academy　of　Sciences.　Publishing　services　by　Elsevier　B.V.　on　behalf　of　KeAi　Communi-cations　Co.,　Ltd.　This　is　an　open　access　article　under　the　CC　BY-NC-ND　license　(http://creativecommons.org/licenses/by-nc-nd/4.0/).