Photoreduction,　especially　laser-reduction,　is　a　clean　and　controllable　micro-and　nano-fabrication　method　which　has　been　applied　in　the　field　of　spectroscopy,　fluorescent　imaging　and　three　dimensional　(3D)　fabrication.　The　in　situ　reduction　of　Ag+　with　ultraviolet　nanosecond　laser　lithography　is　focused,　which　is　much　time-effective　compared　with　two(multi)-photon　absorption　reduction.　Combined　with　ultraviolet　and　visible　light　reduction,　different　sub-micron　gratings　with　large　area　and　different　surface　morphology　are　fabricated.　The　reduction　mechanism　based　on　the　roles　of　laser　reduction　time　is　discussed,　Ag+　concentration　and　light　wavelength.　The　gratings　compose　of　a　large　number　of　close-packed　Ag　nanoparticles　which　are　of　importance　for　surfaceenhanced　Raman　scattering.　The　performance　of　surface-enhanced　Raman　scattering　is　demonstrated　by　tracing　naproxen.　©,　2015,　Science　Press.　All　right　reserved.