Designing　highly　efficient　and　durable　electrode　for　methanol　oxidation　reaction　(MOR)　is　crucial　to　commercializing　direct　methanol　fuel　cells　(DMFCs).　However,　traditional　Pt/C　catalysts　usually　suffer　from　CO　poisoning,　and　agglomeration　of　powder　catalyst,　which　leads　to　rapid　activity　degradation.　Herein,　we　have　successfully　fabricated　self-supported　Pt3Cu@3DP-WO3/W　electrode　via　a　facile　and　effective　synthesis　approach　by　combining　anodic　oxidation　and　electrodeposition　method.　Benefitting　from　the　three　dimensional　nanoporous　of　WO3　with　more　surface　area　and　strong　adhesion,　and　Pt3Cu　alloy　synergism　induced　the　lattice　compressive　strain,　the　Pt3Cu@3DP-WO3/W　electrode　achieved　2.77-fold　and　4.8-fold　enhancement　in　specific　activity　(2.15　mA　cm-2)　and　mass　activity　(853　mA$mgPt-1)　for　MOR　relative　to　Pt/C　catalysts,　respectively.　Moreover,　both　the　experiments　and　theoretical　calculations　revealed　that　the　doping　of　Cu　element　weakened　the　chemisorption　of　CO-like　intermediates　by　lowering　the　Pt　d-band　center　through　compressive　lattice　strain,　which　resulting　in　excellent　catalytic　stability.　This　binder-free　self-supported　electrode　is　a　viable　alternative　for　commercial　application　of　DMFCs.(c)　2023　Hydrogen　Energy　Publications　LLC.　Published　by　Elsevier　Ltd.　All　rights　reserved.