Cardiac　cells　are　assembled　within　a　complicated　microenvironment　possessing　diverse　biochemical　and　biophysical　cues　that　modulate　cellular　behaviors　and　tissue　functions.　Apart　from　the　widely　studied　pathways　of　biochemical　regulation,　positive　effects　of　electrical　cues　on　the　regeneration　of　excitable　cardiac　tissues　have　been　demonstrated.　Conductive　biomaterials　have　emerged　as　important　two-way　media　to　facilitate　the　transmission　of　endogenous　bioelectricity　or　exogenous　electrical　stimuli　strengthening　cardiac　tissue　regeneration,　while　in　the　meantime　allow　online　monitoring　of　bioelectrical　activities.　Mechanical　energy　exists　prevalently　in　the　heart,　which　brings　huge　promise　in　building　a　self-powered,　monitoring　enabled,　on-demand　stimulation　system　by　using　piezoelectric　biomaterials.　In　this　regard,　conductive　biomaterials　and　piezoelectric　biomaterials　synergizing　with　electrostimulation　for　tissue　regeneration　and　function-monitoring　in　cardiac　tissue　engineering　are　comprehensively　reviewed.　After　the　biological　electrical　conduction　system　in　the　human　heart　is　firstly　introduced,　electroactive　biomaterials　that　display　biomimetic　microenvironmental　cues　(e.g.,　electrical,　mechanical,　topological)　and　their　mediated　electrostimulation　are　summarized.　Subse-quently,　the　current　state　in　electroactive　biomaterials　synergizing　with　electrostimulation　for　cardiac　tissue　regeneration　is　systematically　overviewed　together　with　the　underlying　mechanisms　in　modulating　cardiac　cell　activities.　Furthermore,　recent　advances　in　electroactive　biomaterials　used　in　the　online　monitoring　of　cardiac　tissue　function　are　discussed.　Finally,　the　remaining　challenges　in　3D　complex　biomimetic　designs,　systematic　parameter　optimizations　and　cellular　mechanisms,　long-term　electrical　performance,　and　biosafety　are　laid　out,　which　call　for　interdisplinary　joint　forces　in　the　innovation　and　advancement.