Five　tetraphenylethene　(TPE)　derivatives　1a,　1b,　2,　3,　and　4　with　adjustable　stimuli-responsive　characteristics　were　designed　and　synthesized　in　this　study.　Using　single-crystal　X-ray　diffraction,　the　effects　of　substitution　positions　and　pyrazolyl　numbers　on　molecular　packing　were　examined　in　the　solid　state.　The　findings　indicate　that　as　the　pyrazolyl　numbers　increased,　the　molecular　packing　of　the　compound　progressively　changed　from　the　C-　H　&　sdot;&　sdot;&　sdot;pi　stacked　compact　mode　in　1　-　3　to　the　X-crossing　stacked　loose　mode　in　4,　which　results　in　the　origin　of　various　stimuli-responsive　phenomena　in　compound　4.　This　approach　facilitates　the　preparation　of　multi-stimuli-responsive　(thermochromism,　mechanochromism,　and　metal　ion　fluorescence　switch)　smart　fluorophores　with　tunable　emission　color.　Moreover,　compound　4,　with　an　excellent　fluorescence　performance,　exhibited　three　different　colors　when　reversible　mechanochromism　was　selected　as　the　candidate　for　an　optical　recording　material　and　security　ink.　This　study　proposes　an　effective　method　to　guide　the　design　of　stimuli-responsive　materials,　which,　in　turn,　would　facilitate　the　development　of　high-contrast　MC　molecules,　and　the　optical　information　anticounterfeiting　based　on　grinding　was　proven　by　utilizing　the　grindresponsive　luminescence　capabilities.