• Complex
  • Title
  • Keyword
  • Abstract
  • Scholars
  • Journal
  • ISSN
  • Conference
搜索

Author:

Qin, Han (Qin, Han.) | Zhang, Liping (Zhang, Liping.) | Li, Xiaodan (Li, Xiaodan.) | Xu, Zhifei (Xu, Zhifei.) | Zhang, Jie (Zhang, Jie.) | Wang, Shengcai (Wang, Shengcai.) | Zheng, Li (Zheng, Li.) | Ji, Tingting (Ji, Tingting.) | Mei, Lin (Mei, Lin.) | Kong, Yaru (Kong, Yaru.) | Jia, Xinbei (Jia, Xinbei.) | Lei, Yi (Lei, Yi.) | Qi, Yuwei (Qi, Yuwei.) | Ji, Jie (Ji, Jie.) | Ni, Xin (Ni, Xin.) | Wang, Qing (Wang, Qing.) | Tai, Jun (Tai, Jun.)

Indexed by:

Scopus SCIE

Abstract:

Objective The objective of this study was to investigate the effectiveness of a machine learning algorithm in diagnosing OSA in children based on clinical features that can be obtained in nonnocturnal and nonmedical environments.Patients and methods This study was conducted at Beijing Children's Hospital from April 2018 to October 2019. The participants in this study were 2464 children aged 3-18 suspected of having OSA who underwent clinical data collection and polysomnography(PSG). Participants' data were randomly divided into a training set and a testing set at a ratio of 8:2. The elastic net algorithm was used for feature selection to simplify the model. Stratified 10-fold cross-validation was repeated five times to ensure the robustness of the results.Results Feature selection using Elastic Net resulted in 47 features for AHI >= 5 and 31 features for AHI >= 10 being retained. The machine learning model using these selected features achieved an average AUC of 0.73 for AHI >= 5 and 0.78 for AHI >= 10 when tested externally, outperforming models based on PSG questionnaire features. Linear Discriminant Analysis using the selected features identified OSA with a sensitivity of 44% and specificity of 90%, providing a feasible clinical alternative to PSG for stratifying OSA severity.Conclusions This study shows that a machine learning model based on children's clinical features effectively identifies OSA in children. Establishing a machine learning screening model based on the clinical features of the target population may be a feasible clinical alternative to nocturnal OSA sleep diagnosis.

Keyword:

children obstructive sleep apnea artificial intelligence machine learning computer-aided diagnosis

Author Community:

  • [ 1 ] [Qin, Han]Chinese Acad Med Sci & Peking Union Med Coll, Childrens Hosp Capital Inst Pediat, Capital Inst Pediat, Dept Child Hlth Care, Beijing, Peoples R China
  • [ 2 ] [Kong, Yaru]Chinese Acad Med Sci & Peking Union Med Coll, Childrens Hosp Capital Inst Pediat, Capital Inst Pediat, Dept Child Hlth Care, Beijing, Peoples R China
  • [ 3 ] [Jia, Xinbei]Chinese Acad Med Sci & Peking Union Med Coll, Childrens Hosp Capital Inst Pediat, Capital Inst Pediat, Dept Child Hlth Care, Beijing, Peoples R China
  • [ 4 ] [Zhang, Liping]Cross Strait Tsinghua Res Inst, Pharmacovigilance Res Ctr Informat Technol & Data, Xiamen, Peoples R China
  • [ 5 ] [Wang, Qing]Cross Strait Tsinghua Res Inst, Pharmacovigilance Res Ctr Informat Technol & Data, Xiamen, Peoples R China
  • [ 6 ] [Li, Xiaodan]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
  • [ 7 ] [Zhang, Jie]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
  • [ 8 ] [Wang, Shengcai]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
  • [ 9 ] [Zheng, Li]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
  • [ 10 ] [Ji, Tingting]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
  • [ 11 ] [Mei, Lin]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
  • [ 12 ] [Ji, Jie]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
  • [ 13 ] [Ni, Xin]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
  • [ 14 ] [Xu, Zhifei]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Resp Dept, Beijing, Peoples R China
  • [ 15 ] [Lei, Yi]Beijing Univ Technol, Fac Informat Technol, Beijing, Peoples R China
  • [ 16 ] [Qi, Yuwei]Childrens Hosp, Dept Otolaryngol Head & Neck Surg, Capital Inst Pediat, Beijing, Peoples R China
  • [ 17 ] [Tai, Jun]Childrens Hosp, Dept Otolaryngol Head & Neck Surg, Capital Inst Pediat, Beijing, Peoples R China
  • [ 18 ] [Wang, Qing]Tsinghua Univ, Dept Automat, BNRIST, Beijing, Peoples R China

Reprint Author's Address:

  • [Wang, Qing]Cross Strait Tsinghua Res Inst, Pharmacovigilance Res Ctr Informat Technol & Data, Xiamen, Peoples R China;;[Ni, Xin]Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China;;[Tai, Jun]Childrens Hosp, Dept Otolaryngol Head & Neck Surg, Capital Inst Pediat, Beijing, Peoples R China;;[Wang, Qing]Tsinghua Univ, Dept Automat, BNRIST, Beijing, Peoples R China

Show more details

Related Keywords:

Related Article:

Source :

FRONTIERS IN PEDIATRICS

ISSN: 2296-2360

Year: 2024

Volume: 12

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count: 3

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

Affiliated Colleges:

Online/Total:630/5319460
Address:BJUT Library(100 Pingleyuan,Chaoyang District,Beijing 100124, China Post Code:100124) Contact Us:010-67392185
Copyright:BJUT Library Technical Support:Beijing Aegean Software Co., Ltd.