E-waste　dismantling　has　induced　the　surrounding　farmland　subjected　to　combined　contamination　of　heavy　metals　(HMs)　and　organic　pollutants.　At　present,　applicable　regimes　for　safety　production　of　the　contaminated　paddy　soils　and　involving　mechanisms　are　still　unclear.　Here,　we　investigated　the　effects　of　three　soil　conditioners　(lime,　biochar,　and　fengshouyan)　on　paddy　soil　ecosystem.　Results　showed　that　lime　amendments　reduced　the　migration　of　Cd　and　As　to　rice　grains.　While　biochar　incorporation　increased　the　concentration　of　Cd　in　the　polished　grains　by　29.14　%.　Statistical　analyses　indicated　soil　microbiome　substantially　contributed　to　the　accumulation　of　Cd　and　As　in　the　polished　grains.　Variables　measured　at　the　maturation　and　filling　stage　explained　more　changes　of　Cd　and　As　in　the　maturation　polished　grains,　respectively.　Together,　lime　was　the　best　soil　conditioner.　Future　research　might　further　increase　food　security　by　regulation　on　soil　biotics　at　specific　stage　and　eventually　realize　sustainable　development　of　e　-waste　dismantling.