The　present　work　reported　the　space　confinement　effect　of　carbon　nanotube-alumina　strip　(CAS)　support　on　the　Cu-Co　bimetallic　catalyst　or　the　single　Cu,　Co　catalysts　for　the　CO2　methanation.　CAS,　made　by　extrusion　of　nanotubes　and　Al-based　sol　and　high　temperature　calcination,　was　a　macroscopic　support　with　sufficient　mesopores　and　hydrophobic　property.　Cu-Co/CAS　catalysts　exhibited　high　catalytic　activity　for　methanation　of　CO2　(H-2/CO2=3:1),　where　CO2　conversion　was　49.62%　and　CH4　selectivity　was　95.98%　at　temperature　as　low　as　250　degree　celsius　and　1.5　MPa,　and　showed　advantage　significantly　over　those　with　the　supports　of　individual　nanotube　or　pure　Alumina　support.　The　comparison　suggested　the　hydrophobicity　of　carbon　nanotubes　can　effectively　remove　water　from　the　metal　active　sites,　enhancing　the　equilibrium　of　reverse　water　gas　shift　and　CO　methanation　reactions,　as　compared　to　alumina　support.　Additionally,　CAS　support　had　a　spatial　confinement　effect　that　increased　the　contact　time　of　CO2　or　intermediates　with　the　active　sites,　compared　with　individual　nanotube　support.　XPS　and　Raman　spectroscopy　validated　the　presence　of　oxygen　vacancies　of　CAS,　promoting　the　CO2　methanation.　H-2-TPR　results,　in　combination　with　DFT　calculations,　confirmed　that　the　CAS　supports　enabled　the　Cu-Co　active　phase　by　changing　their　electronic　structures,　to　possess　a　strong　adsorption　activation　capacity　for　H-2　at　low　temperatures　with　high　performance　for　CO2　methanation.