The　development　of　biofunctional　coating　is　vital　for　the　clinical　application　of　implants.　A　persistent　challenge　with　magnesium　alloys　implants,　which　are　inherently　prone　to　rapid　degradation,　is　the　simultaneously　enhancement　of　corrosion　resistance　and　bioactivity.　This　study　introduces　a　novel　protein　coating　for　magnesium　alloys,　incorporating　calcium　and　strontium　ions　with　silk　fibroin.　By　utilizing　the　microcrystal　nucleation　facilitated　by　a　binary　solvent　system,　the　fl-sheet　content　is　significantly　increased　to　45.4　%　in　silk　fibroin.　The　increased　fl-sheet　bolsters　the　＂labyrinth　effect＂　at　the　nanoscale,　resulting　in　a　substantial　improvement　in　corrosion　resistance.　This　is　evidenced　by　a　three-order-of-magnitude　reduction　in　the　corrosion　current　density　(Icorr)　to　3.65　x　10-7　A　cm-2,　compared　to　that　of　the　uncoated　alloys.　The　meticulous　doping　of　Ca2+　and　Sr2+　ions　ensures　stable　chelation　with　amorphous　segments　of　silk　fibroin.　The　controlled　release　activates　the　Wnt　signaling　pathway,　boosting　osteogenic　activity.　Such　silk　fibroin　coating　system,　prepared　through　a　straightforward　method,　enables　a　concurrent　enhancement　of　both　corrosion　resistance　and　osteogenic　potential　in　biomedical　magnesium　alloys.