Mode　analysis　and　dynamic　time-history　analysis　are　used　to　investigate　the　steel　frame-tube　structure　and　steel　frame-tube　structure　with　cross　layer　pre-stressed　inclined　brace.　The　development　of　the　plastic　hinge　and　parameters　of　the　two　structures,　such　as　inter-story　displacement　angle,　top　lateral,　base　shear,　etc,　are　compared.　The　influence　of　cross　layer　pre-stressed　brace　on　seismic　performance　of　steel　frame-tube　structure　is　studied.　Results　show　that　applying　the　cross　layer　pre-stressed　brace,　the　seismic　performance　of　steel　frame-tube　structure　is　improved　obviously.　©,　2014,　Tianjin　University.　All　right　reserved.