The　objective　of　this　work　was　to　investigate　the　effectiveness　of　ozonation　on　the　removal　of　organic　residues　and　pathogenic　microorganism　from　the　municipal　secondary　effluent.　The　DOC,　UV254,　chroma,　di-n-butyl　phthalate　(DBP),　di-2-ethylhexyl　phthalate　(DEHP)　and　organic　pollutants　of　three-dimensional　fluorescence　removals　of　ozonation　were　15.49%,　36.36%,　73.61%,　37.29%,　14.6%　and　above　80%　at　a　dose　of　6　mg/L,　respectively.　And　the　ozonated　secondary　effluent　concentration　of　DBP　and　DEHP　was　2.64　μg/L　and　1.4　μg/L,　respectively,　which　meets　the　standard　of　the　Reuse　of　Urban　Recycling　Water　Quality　Standard　for　Groundwater　Recharge　(GB/T　19772-2005).　The　fecal　coliforms　were　close　to　103CFU/L　and　10CFU/L　by　ozonation　(at　a　ozone　dose　of　10　mg/L)　and　chlorination　(at　a　available　chlorine　dose　of　5　mg/L),　respectively.　However,　the　combination　of　ozonation　(at　a　ozone　dose　of　6　mg/L)　and　chlorination　(at　a　available　chlorine　dose　of　5　mg/L)　led　to　an　increased　removal　of　fecal　coliforms　of　3CFU/L,　which　meets　the　standard　of　the　Reuse　of　Urban　Recycling　Water-Water　Quality　Standard　for　Scenic　Environment　Use　(GB/T　18921-2002).　The　generation　of　trihalomethanes　(THMs)　increased　with　the　increase　of　available　chlorine　dosage,　while　it　was　reduced　by　78.08%　by　using　the　combination　of　ozonation　and　chlorination.