A　design　for　modified　planar　passive　micromixer　based　on　the　concept　of　vortex-generated　structure　enhanced　mixing　is　described　in　this　work.　By　using　computational　fluid　dynamics　CFD-ACE+,　three-dimensional　numerical　simulation　and　structural　optimization　for　mixing　were　performed　in　order　to　reveal　the　structural　influence　on　the　flow　feature　and　mixing　characteristics.　Experimental　data　were　used　to　validate　the　numerical　analysis.　The　computational　and　experimental　results　for　the　concentration　distributions　and　flow　patterns　demonstrate　that　the　expansion　vortices,　separated　vortices　and　Dean　vortices　appear　in　the　curved　channel　of　this　modified　micromixer,　which　is　arranged　to　vortex-generated　structures.　The　combination　and　enhancement　of　the　vortex　system　increase　the　fluid　disturbance,　effectively　improving　the　contact　area　of　fluid　and　accelerating　the　mixing　process.　Based　on　comprehensive　consideration　of　mixing　efficiency　and　pressure　drop　distribution,　the　structural　design　adopts　the　vortex-generated　structure　with　regular　arrangement,　and　the　gap　width　ratio　Wd/W,　thickness-width　ratio　B/W,　and　arrangement　angle　θa　are　equal　to　1/4,　3/10,　and　120°,　respectively.　Significant　mixing　effect　of　fluid　in　the　micromixer　can　be　realized　in　a　wide　range　of　Reynolds　number.　©　All　Rights　Reserved.