This　paper　studies　the　fault　detection　and　isolation　problem　for　uncertain　flight　control　systems　with　actuator　outage　faults,　which　has　not　been　well　investigated　in　the　literature.　A　state　feedback　controller　and　a　detection　weighting　matrix　are　designed　simultaneously,　through　which　the　closed-loop　system　is　stabilized　for　both　fault-free　and　actuator　outage　cases,　and　the　actuator　outage　faults　can　be　detected　through　the　residual　signal　generated　by　recombining　system　states　with　the　detection　weighting　matrix.　Additionally,　a　set　of　isolation　weighting　matrices　are　designed　to　identify　the　locations　of　the　actuators　that　are　of　outage.　A　VTOL　aircraft　model　is　given　to　illustrate　the　effectiveness　of　the　proposed　methods.