Thermal-fluid　transport　in　the　pipeline　is　an　essential　process　in　the　application　of　chemical　industry,　biology　and　microfluidic　chip.　Conventional　fluid　transport　in　the　pipeline　generates　much　energy　loss　by　hysteresis　and　heat　transfer　at　the　solid/liquid　interface,　which　has　become　the　most　significant　issue　for　the　applications　of　novel　energy-efficient　equipments.　Here,　we　demonstrate　a　flexible　superhydrophobic　pipeline　with　fluid-resistance　reduction　and　thermal　isolation　properties.　Liquid　metal　as　buffer　material　enhances　the　bonding　strength　between　flexible　pipeline　and　nano-structures,　providing　much　more　pocketed　air　between　solid/liquid　interface,　which　enhances　the　water　repellency　of　inwall　surface　and　declines　the　interfacial　heat　transfer　efficiency.　These　research　highlights　the　potential　applications　of　superhydrophobic　functional　materials　in　the　field　of　energy　conservation　and　environment　protection.