A　high-Ti　6061　alloy　was　rolled　with　strains　up　to　0.8-2.0　and　at　350-550°C.　Microstructures　that　developed　during　deformation　and　subsequent　solution　heat　treatment　(SHT)　were　observed　by　using　optical　and　transmission　electron　microscopy.　Microstructure　evolution　during　SHT　depends　mainly　on　the　initial　rolling　temperature,　and　it　was　found　that　the　higher　this　temperature　is,　the　coarser　the　grains　are.　After　rolling　at　400°C,　well-defined　cells　and　subgrains　were　formed,　which　induced　further　sites　for　recrystallization　nucleation　during　subsequent　SHT.　The　recrystallization　mechanism　was　found　to　be　subgrain　rotation,　with　a　final　grain　size　smaller　than　200　μm.　Increasing　the　rolling　temperature　to　500°C　results　in　a　low　density　of　dislocations　distributed　uniformly　in　the　deformed　matrix　and　fewer　nucleation　sites　during　subsequent　SHT.　The　recrystallization　mechanism　is　grain　boundary　bulging,　while　the　final　grain　size　approaches　several　millimeters.　Finally,　a　hot　forming　process　of　high-Ti　6061　alloy　for　inhibiting　grain　coarsening　was　proposed,　and　verified　by　experiments.