To　increases　cation　exchange　capacity　(CEC),　Ca-montmorillonite　is　exchanged　upon　Ca2+　and　Mg2+　to　Na+　and　forms　Na-montmorillonite.　Al　pillared　montmorillonite　(Al-PILCS)　support　is　prepared　by　the　intercalation　of　polymerization　of　aluminum　hydroxyl　ions　(Al-agent)　with　Na-montmorillonite　and　then　calcined.　Platinum　and　gold　is　deposited　on　Al-PILCS　by　deposition-precipitation　(DP)　and　impregnation.　The　characterization　and　catalytic　activity　of　the　samples　are　investigated　by　X-ray　diffraction　(XRD),　N2-sorption　analysis,　transmission　electron　microscopy　(TEM),　X-ray　photoelectron　spectroscopy　(XPS)　techniques,　and　CO　oxidation　reaction.　Results　of　XRD　and　N2-desorption/adsorption　show　that　due　to　pillaring,　Al-PILCS　in　microporous　surface　area　and　micropore　volume　increase　distinctively.　The　influence　of　the　preparation　methods　on　the　catalytic　activity　for　CO　oxidation　is　markedly　large　for　Au/Al-PILCS　and　negligible　for　Pt/Al-PILCS　catalysts.　The　DP　method　gives　the　most　active　catalysts　for　both　Pt　and　Au.　Pt　catalysts　prepared　by　DP　show　a　much　greater　activity　than　Au　catalysts.　Different　activities　of　Au/Al-PILCS　and　Pt/Al-PILCS　may　attribute　to　two　reasons:　the　size　of　Au　and　Pt　parties,　and　different　reaction　mechenismes.　XPS　techniques　verified　that　the　Au　species　of　the　samples　is　only　metal　Au0　over　Au/Al-PILCS-IM　and　oxidation　state　Auδ+　and　metal　Au0　coexist　over　Au/Al-PILCS-DP.