Stent　intervention　has　become　one　of　the　most　effective　ways　in　treating　cardiac　and　cerebral　vascular　stenosis.　However,　postoperative　in-stent　restenosis　remains　a　major　unsettled　issue.　The　occurrence　of　in-stent　restenosis　is　related　not　only　to　the　mismatch　between　stent　and　artery,　as　well　as　the　stress　induced　by　mechanical　support　of　the　stent　struts　on　arterial　wall,　but　also　to　the　intimal　hyperplasia　induced　by　the　hemodynamic　change.　Recent　literatures　on　biomechanics　of　the　stented　artery　were　reviewed　in　this　paper.　In　particular,　from　the　view　of　solid　mechanics　and　hemodynamics,　the　research　progress　of　stented　artery　in　biomechanical　simulation　was　given　detailed　discussion;　moreover,　the　biomechanical　factors　associated　with　in-stent　restenosis　were　analyzed　and　summarized.　Numerical　simulation　is　a　good　method　for　investigating　the　relationship　between　stent　intervention　and　in-stent　restenosis,　and　it　also　provides　a　scientific　guideline　for　the　design　of　stent　structure　and　clinical　procedure　of　stent　intervention.