Anaerobic　ammonia　oxidation　(anammox)　and　denitrification　can　work　together　to　weaken　the　influence　of　organic　matter　on　anaerobic　ammonia　oxidation　bacteria　(AAOB)　and　improve　nitrogen　removal　performance.　As　the　common　substrate　of　anammox　and　denitrification,　nitrite　will　also　affect　nitrogen　removal　performance　when　it　is　insufficient,　which　is　not　conducive　to　reflect　the　endurance　of　anammox　reactor　to　organic　matter.　The　UASB　continuous　flow　experiment　was　carried　out　to　investigate　the　effect　of　the　concentration　of　glucose　and　sodium　acetate　on　nitrogen　removal　performance　of　anammox　reactor　under　the　condition　of　sufficient　nitrite.　With　glucose　as　the　organic　matter,　when　the　chemical　oxygen　demand　(COD)　concentration　increased　to　200　mg　l(-1),　nitrogen　removal　performance　of　the　system　began　to　deteriorate　significantly,　and　the　anammox　activity　was　significantly　inhibited.　With　sodium　acetate　as　the　organic　substance,　the　anammox　activity　was　affected　when　the　COD　was　20　mg　l(-1).　Adequate　nitrite　could　relieve　the　inhibition　of　the　coupling　system　by　a　low　concentration　(COD　＜　200　mg　l(-1))　of　glucose　organic　matter.　However,　it　could　not　relieve　the　inhibitory　effect　of　sodium　acetate.　With　the　increase　of　organic　concentration,　the　biological　density　of　AAOB　in　granular　sludge　gradually　decreased,　while　the　biological　density　of　denitrifying　bacteria　increased　gradually.