Aiming　at　the　problems　that　3D　user　interface　configuration　process　was　complicated　and　human-computer　interaction　was　not　natural,　which　hampered　the　application　of　3D　configuration　software,　a　3D　user　interface　configuration　method　based　on　semantic　virtual　connector　was　proposed.　By　building　the　virtual　scene　modeling　ontology,　the　method　could　make　the　human-computer　interaction　in　3D　user　interface　configuration　more　easier　with　the　aid　of　ontology　semantic　information.　The　virtual　connector　concept　was　presented.　As　a　carrier　of　the　semantic　information　of　human-computer　interaction,　virtual　connectors　were　used　to　represent　the　possible　connection　relationships　in　scene　objects.　The　automatic　configuration　connection　between　the　scene　objects　was　realized,　and　then　users　could　perform　complex　modeling　task　through　the　simple　human-computer　interaction.　The　validity　of　this　method　was　verified　by　the　3D　configuration　software　prototype　system　in　chemical　field.