We　propose　a　new　method　of　annotating　a　masterpiece　of　traditional　Chinese　painting　with　voice　dubbings　and　environmental　sounds.　The　painting　was　created　with　moving　focus　drawing　technique　without　rigorous　perspective.　A　novel　algorithm　is　proposed　to　infer　the　3D　space　of　the　painting　according　to　its　layout　and　embed　the　audio　annotations.　For　exhibition,　the　masterpiece　is　scanned　into　a　high-resolution　gigapixel　image　for　presenting　the　drawing　details,　and　we　develop　an　interactive　multimedia　system　with　a　panning　and　zooming　interface　to　enable　smooth　navigation　on　the　giant　painting　and　exploring　the　historical　culture.　During　the　navigation,　the　system　estimates　the　3D　position　of　the　user＇s　viewpoint　from　his/her　actions,　and　subsequently　synthesizes　a　realistic　stereo　audio　field　according　to　the　viewer＇s　orientation　and　distance　from　the　annotations　in　the　3D　space.　The　proposed　system　provides　an　immersive　user　experience　by　rendering　a　visual-audio　consistent　perception.　©　2012　ACM　1556-4673/2012/07-ART6　$15.00.